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Article

CryoEM structure of the super-constricted two-start dynamin 1 filament.

Nature communications - 13 Sept 2021

Liu Jiwei, Alvarez Frances Joan D, Clare Daniel K, Noel Jeffrey K, Zhang Peijun

Abstract excerpt

Dynamin belongs to the large GTPase superfamily, and mediates the fission of vesicles during endocytosis. Dynamin molecules are recruited to the neck of budding vesicles to assemble into a helical collar and to constrict the underlying membrane. Two helical forms were observed: the one-start helix in the constricted state and the two-start helix in the super-constricted state. Here we report the cryoEM structure...

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Identifiers

PMID: 34518553
DOI: 10.1038/s41467-021-25741-x
PMCID: PMC8437954

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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