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Article

Cryo-EM of the dynamin polymer assembled on lipid membrane.

Nature - 1 Aug 2018

Kong Leopold, Sochacki Kem A, Wang Huaibin, Fang Shunming, Canagarajah Bertram, Kehr Andrew D, Rice William J, Strub Marie-Paule, Taraska Justin W, Hinshaw Jenny E

Abstract excerpt

Membrane fission is a fundamental process in the regulation and remodelling of cell membranes. Dynamin, a large GTPase, mediates membrane fission by assembling around, constricting and cleaving the necks of budding vesicles1. Here we report a 3.75 Å resolution cryo-electron microscopy structure of the membrane-associated helical polymer of human dynamin-1 in the GMPPCP-bound state. The structure defines the...

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Identifiers

PMID: 30069048
DOI: 10.1038/s41586-018-0378-6
PMCID: PMC6121775

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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