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Article

Crystal structure of the dynamin tetramer.

Nature - 17 Sept 2015

Reubold Thomas F, Faelber Katja, Plattner Nuria, Posor York, Ketel Katharina, Curth Ute, Schlegel Jeanette, Anand Roopsee, Manstein Dietmar J, Noé Frank, Haucke Volker, Daumke Oliver, Eschenburg Susanne

Abstract excerpt

The mechanochemical protein dynamin is the prototype of the dynamin superfamily of large GTPases, which shape and remodel membranes in diverse cellular processes. Dynamin forms predominantly tetramers in the cytosol, which oligomerize at the neck of clathrin-coated vesicles to mediate constriction and subsequent scission of the membrane. Previous studies have described the architecture of dynamin dimers, but the...

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Identifiers

PMID: 26302298
DOI: 10.1038/nature14880

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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