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Article

Comparative analysis of the ex vivo IFN-gamma responses to CD8+ T cell epitopes within allelic forms of PfAMA1 in subjects with natural exposure to malaria.

PloS one - 1 Jan 2021

Nlinwe Omarine N, Ofori Ebenezer A, Akyea-Mensah Kwadwo, Kyei-Baafour Eric, Ganeshan Harini, Belmonte Maria, Peters Bjoern, Villasante Eileen, Sedegah Martha, Kusi Kwadwo Asamoah

Abstract excerpt

Antigen polymorphisms in essential malarial antigens are a key challenge to the design and development of broadly effective malaria vaccines. The effect of polymorphisms on antibody responses is fairly well studied while much fewer studies have assessed this for T cell responses. This study investigated the effect of allelic polymorphisms in the malarial antigen apical membrane antigen 1 (AMA1) on ex vivo T...

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Share to Antigens, Protozoan
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Malaria, Falciparum

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Source

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Identifiers

PMID: 34506564
DOI: 10.1371/journal.pone.0257219
PMCID: PMC8432784

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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