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Article

Humoral immune responses to a single allele PfAMA1 vaccine in healthy malaria-naïve adults.

PloS one - 1 Jan 2012

Remarque Edmond J, Roestenberg Meta, Younis Sumera, Walraven Vanessa, van der Werff Nicole, Faber Bart W, Leroy Odile, Sauerwein Robert, Kocken Clemens H M, Thomas Alan W

Abstract excerpt

UNLABELLED: Plasmodium falciparum: apical membrane antigen 1 (AMA1) is a candidate malaria vaccine antigen expressed on merozoites and sporozoites. The polymorphic nature of AMA1 may compromise vaccine induced protection. The humoral response induced by two dosages (10 and 50 µg) of a single allele AMA1 antigen (FVO) formulated with Alhydrogel, Montanide ISA 720 or AS02 was investigated in 47 malaria-naïve adult...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22768052
DOI: 10.1371/journal.pone.0038898
PMCID: PMC3387192

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