Article
Comparison of the impact of allelic polymorphisms in PfAMA1 on the induction of T Cell responses in high and low malaria endemic communities in Ghana.
Malaria journal - 10 Sept 2021
Ofori Ebenezer A, Tetteh John K A, Frimpong Augustina, Ganeshan Harini, Belmonte Maria, Peters Bjoern, Villasante Eileen, Sedegah Martha, Ofori Michael F, Kusi Kwadwo A
Abstract excerpt
BACKGROUND: Malaria eradication requires a combined effort involving all available control tools, and these efforts would be complemented by an effective vaccine. The antigen targets of immune responses may show polymorphisms that can undermine their recognition by immune effectors and hence render vaccines based on antigens from a single parasite variant ineffective against other variants. This study compared...
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