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Article

Alternative Splicing and Hypoxia Puzzle in Alzheimer’s and Parkinson’s Diseases

20 Aug 2021

Abstract excerpt

Alternative pre-mRNA splicing plays a very important role in expanding protein diversity as it generates numerous transcripts from a single protein-coding gene. Therefore, alterations lead this process to neurological human disorders, including Alzheimer's and Parkinson's diseases. Moreover, accumulating evidence indicates that the splicing machinery highly contributes to the cells' ability to adapt to different...

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PMID: 34440445
DOI: 10.3390/genes12081272

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