Article
Aberrant splicing in neurological diseases.
Wiley interdisciplinary reviews. RNA - 1 Jan 2000
Feng Dairong, Xie Jiuyong
Abstract excerpt
Splicing of precursor messenger RNA (pre-mRNA) removes the intervening sequences (introns) and joins the expressed regions (exons) in the nucleus, before an intron-containing eukaryotic mRNA transcript can be exported and translated into proteins in the cytoplasm. While some sequences are always included or excluded (constitutive splicing), others can be selectively used (alternative splicing) in this process....
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