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Neurodegenerative diseases: a hotbed for splicing defects and the potential therapies

20 May 2021

Abstract excerpt

Precursor messenger RNA (pre-mRNA) splicing is a fundamental step in eukaryotic gene expression that systematically removes non-coding regions (introns) and ligates coding regions (exons) into a continuous message (mature mRNA). This process is highly regulated and can be highly flexible through a process known as alternative splicing, which allows for several transcripts to arise from a single gene, thereby...

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Neurogenetic and Muscular Disorders Research
RNA regulation and disease
RNA Research and Splicing

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34016162
DOI: 10.1186/s40035-021-00240-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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