Article
Alternative splicing in the nervous system: an emerging source of diversity and regulation.
Biological psychiatry - 15 Oct 2003
Lee Christopher J, Irizarry Kris
Abstract excerpt
Alternative splicing is emerging as a major mechanism of functional regulation in the human genome. Previously considered to be an unusual event, it has been detected by many genomics studies in 40%-60% of human genes. Moreover, it appears to be of central importance for neuronal genes and other genes involved in "information processing" functions. In this review, we will summarize alternative splicing's effects...
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