Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Splicing and neurodegeneration: Insights and mechanisms

20 Mar 2019

Abstract excerpt

Splicing is the global cellular process whereby intervening sequences (introns) in precursor messenger RNA (pre-mRNA) are removed and expressed regions (exons) are ligated together, resulting in a mature mRNA transcript that is exported and translated in the cytoplasm. The tightly regulated splicing cycle is also flexible allowing for the inclusion or exclusion of some sequences depending on the specific cellular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neurogenetic and Muscular Disorders Research
Share to RNA modifications and cancer
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30895702
DOI: 10.1002/wrna.1532

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 19 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Splicing and neurodegeneration: Insights and mechanismsPMID 30895702Read ↗

Neurodegenerative diseases: a hotbed for splicing defects and the potential therapiesSemantic proximity Read ↗

Aberrant splicing in neurological diseases.Semantic proximity Read ↗

The Impact of Splicing Dysregulation on Neuromuscular Disorders and Current Neuromuscular Genetic TherapiesSemantic proximity Read ↗

Mechanisms of Neuronal Alternative Splicing and Strategies for Therapeutic InterventionsSemantic proximity Read ↗

Alternative splicing in neurodegenerative disease and the promise of RNA therapiesSemantic proximity Read ↗

[Pre-mRNA splicing: when the spliceosome loses ground].Semantic proximity Read ↗

The emerging role of minor intron splicing in neurological disordersSemantic proximity Read ↗

Alternative splicing in the nervous system: an emerging source of diversity and regulation.Semantic proximity Read ↗

The pathogenicity of splicing defects: mechanistic insights into pre-mRNA processing inform novel therapeutic approaches.Semantic proximity Read ↗

The pathobiology of splicing.Semantic proximity Read ↗

Targeting RNA splicing for disease therapySemantic proximity Read ↗

Mechanisms and Regulation of Alternative Pre-mRNA Splicing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.