Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Alternative splicing--principles, functional consequences and therapeutic implications].

Deutsche medizinische Wochenschrift (1946) - 1 Feb 2014

Heyd F

Abstract excerpt

Protein-coding genes in higher eukaryotes are transcribed as pre-mRNA in which the coding regions (exons) are separated by non-coding segments (introns). The exons are connected to form the mature mRNA in a process called splicing. In the case of alternative splicing an exon can be either included or skipped from the mature transcript leading to formation of several mRNAs from a single pre-mRNA. As over 90 % of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Exons
Share to Genetic Predisposition to Disease
Share to Genetic Therapy

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Models, Genetic

Share to RNA Splice Sites

Share to RNA Splicing

Share to Spliceosomes

Source

Identifiers

PMID: 24226838
DOI: 10.1055/s-0033-1349570

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Alternative splicing--principles, functional consequences and therapeutic implications].PMID 24226838Read ↗

[Pre-mRNA splicing: when the spliceosome loses ground].Semantic proximity Read ↗

Alternative Splicing and Isoforms: From Mechanisms to DiseasesSemantic proximity Read ↗

Genomics of alternative splicing: evolution, development and pathophysiology.Semantic proximity Read ↗

Function of alternative splicing.Semantic proximity Read ↗

[Pre-mRNA alternative splicing in cancer: functional impact, molecular mechanisms and therapeutic perspectives].Semantic proximity Read ↗

The pathogenicity of splicing defects: mechanistic insights into pre-mRNA processing inform novel therapeutic approaches.Semantic proximity Read ↗

[Alternative splicing regulation: implications in cancer diagnosis and treatment].Semantic proximity Read ↗

Mechanisms and Regulation of Alternative Pre-mRNA Splicing.Semantic proximity Read ↗

[Deregulation of pre-messenger RNA splicing and rare diseases].Semantic proximity Read ↗

Differential splicing, disease and drug targets.Semantic proximity Read ↗

The pathobiology of splicing.Semantic proximity Read ↗

Alternative Splicing in Genetic Diseases: Improved Diagnosis and Novel Treatment Options.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.