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Alternative Splicing and Isoforms: From Mechanisms to Diseases

24 Feb 2022

Abstract excerpt

Alternative splicing of pre-mRNA is a key mechanism for increasing the complexity of proteins in humans, causing a diversity of expression of transcriptomes and proteomes in a tissue-specific manner. Alternative splicing is regulated by a variety of splicing factors. However, the changes and errors of splicing regulation caused by splicing factors are strongly related to many diseases, something which represents...

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PMID: 35327956
DOI: 10.3390/genes13030401

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