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Article

Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases.

Nature communications - 20 Aug 2021

Kapoor Manav, Chao Michael J, Johnson Emma C, Novikova Gloriia, Lai Dongbing, Meyers Jacquelyn L, Schulman Jessica, Nurnberger John I, Porjesz Bernice, Liu Yunlong, Foroud Tatiana, Edenberg Howard J, Marcora Edoardo, Agrawal Arpana, Goate Alison

Abstract excerpt

Identification of causal variants and genes underlying genome-wide association study (GWAS) loci is essential to understand the biology of alcohol use disorder (AUD) and drinks per week (DPW). Multi-omics integration approaches have shown potential for fine mapping complex loci to obtain biological insights to disease mechanisms. In this study, we use multi-omics approaches, to fine-map AUD and DPW associations...

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Share to Alcoholism
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34417470
DOI: 10.1038/s41467-021-25392-y
PMCID: PMC8379159

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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