Article

Multi-omics integration analysis identifies novel genes for alcoholism with potential link to neurodegenerative diseases

2020-10-16

Abstract excerpt

<h4>Significance</h4> Identification of causal variants and genes underlying genome-wide association study (GWAS) loci is essential to understanding the biology of alcohol use disorder (AUD). <h4>Methods</h4> Integration of “multi-omics” data is often necessary to nominate candidate causal variants and genes and prioritize them for follow up studies. Here, we used Mendelian randomization to integrate AUD and dri...

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Literature Corpus work: 83042e92-a24d-50ad-ac66-5b2b332d444a
DOI: 10.1101/2020.10.15.341750

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