Article
Human genetics and epigenetics of alcohol use disorder.
The Journal of clinical investigation - 15 Aug 2024
Zhou Hang, Gelernter Joel
Abstract excerpt
Alcohol use disorder (AUD) is a prominent contributor to global morbidity and mortality. Its complex etiology involves genetics, epigenetics, and environmental factors. We review progress in understanding the genetics and epigenetics of AUD, summarizing the key findings. Advancements in technology over the decades have elevated research from early candidate gene studies to present-day genome-wide scans, unveiling...
Topics
- Humans
- Epigenesis, Genetic
- Alcoholism
- Genome-Wide Association Study
- Genetic Predisposition to Disease
