Article
Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.
Molecular psychiatry - 1 Jan 2014
Gelernter J, Kranzler H R, Sherva R, Almasy L, Koesterer R, Smith A H, Anton R, Preuss U W, Ridinger M, Rujescu D, Wodarz N, Zill P, Zhao H, Farrer L A
Abstract excerpt
We report a GWAS of alcohol dependence (AD) in European-American (EA) and African-American (AA) populations, with replication in independent samples of EAs, AAs and Germans. Our sample for discovery and replication was 16 087 subjects, the largest sample for AD GWAS to date. Numerous genome-wide significant (GWS) associations were identified, many novel. Most associations were population specific, but in several...
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