Article
Genomic approaches to explore susceptibility and pathogenesis of alcohol use disorder and alcohol-associated liver disease.
Hepatology (Baltimore, Md.) - 1 May 2025
Norden-Krichmar Trina M, Rotroff Daniel, Schwantes-An Tae-Hwi, Bataller Ramon, Goldman David, Nagy Laura E, Liangpunsakul Suthat
Abstract excerpt
Excessive alcohol use is a major risk factor for the development of an alcohol use disorder (AUD) and contributes to a wide variety of other medical illnesses, including alcohol-associated liver disease (ALD). Both AUD and ALD are complex and causally interrelated diseases, and multiple factors other than alcohol consumption are implicated in the disease pathogenesis. While the underlying pathophysiology of AUD...
Topics
- Humans
- Liver Diseases, Alcoholic
- Genetic Predisposition to Disease
- Alcoholism
- Genome-Wide Association Study
- Genomics