Article

Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism

2018-12-19

Abstract excerpt

<h4>ABSTRACT</h4> Alcohol exposure triggers changes in gene expression and biological pathways in human brain. We explored alterations in gene expression in the Pre-Frontal Cortex (PFC) of 65 alcoholics and 73 controls of European descent, and identified 129 genes that showed altered expression (FDR < 0.05) in subjects with alcohol dependence. Differentially expressed genes were enriched for pathways related to i...

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Literature Corpus work: 4c8f1c6e-51fd-5d10-87ce-3ca5453cbf65
DOI: 10.1101/500439

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