Article

Identification of Novel Loci and Cross-Disorder Pleiotropy Through Multi-Ancestry Genome-Wide Analysis of Alcohol Use Disorder in Over One Million Individuals

2023-12-22

Abstract excerpt

<title>Abstract</title> <p>Alcohol use disorder (AUD) is highly heritable and burdensome worldwide. Genome-wide association studies (GWASs) can provide new evidence regarding the aetiology of AUD. We report a multi-ancestry GWASs across diverse ancestries focusing on a narrow AUD phenotype, using novel statistical tools in a total sample of 1,041,450 individuals [102,079 cases; European, 75,583; African, 20,689 (...

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Literature Corpus work: 61a9aa44-e5be-516c-8b4b-aa979575b4fe
DOI: 10.21203/rs.3.rs-3755915/v1

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