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Article

Whole exome sequencing analysis identifies genes for alcohol consumption.

Nature communications - 10 Jul 2024

Kang Jujiao, Deng Yue-Ting, Wu Bang-Sheng, Liu Wei-Shi, Li Ze-Yu, Xiang Shitong, Yang Liu, You Jia, Gong Xiaohong, Jia Tianye, Yu Jin-Tai, Cheng Wei, Feng Jianfeng

Abstract excerpt

Alcohol consumption is a heritable behavior seriously endangers human health. However, genetic studies on alcohol consumption primarily focuses on common variants, while insights from rare coding variants are lacking. Here we leverage whole exome sequencing data across 304,119 white British individuals from UK Biobank to identify protein-coding variants associated with alcohol consumption. Twenty-five variants...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38982111
DOI: 10.1038/s41467-024-50132-3
PMCID: PMC11233704

Genes

GIGYF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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