Article

Multi-omics analyses cannot identify true-positive novel associations from underpowered genome-wide association studies of four brain-related traits

2022-04-14

Abstract excerpt

<h4>Background</h4> The integration of multi-omics information (e.g., epigenetics and transcriptomics) can be useful for interpreting findings from genome-wide association studies (GWAS). It has additionally been suggested that multi-omics may aid in novel variant discovery, thus circumventing the need to increase GWAS sample sizes. We tested whether incorporating multi-omics information in earlier and smaller si...

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Literature Corpus work: 8f071735-dd19-5a7e-9368-27791498aa99
DOI: 10.1101/2022.04.13.487655

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