Article
The current role of NLRP3 inflammasome polymorphism in gout susceptibility.
International journal of rheumatic diseases - 1 Oct 2021
Clavijo-Cornejo Denise, Hernández-González Olivia, Gutierrez Marwin
Abstract excerpt
INTRODUCTION: The NLR family pyrin domain containing 3 (NLRP3) signaling pathway has an important role in inflammation mediated by monosodium urate crystals in gout, and the characterization of single nucleotide polymorphisms (SNPs) have helped to recognize disease susceptibility. OBJECTIVE: The aim of this review is to provide an overview of the potential role of the inflammasome gene SNPs as a susceptibility...
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