Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NALP3 inflammasome functional polymorphisms and gout susceptibility.

Cell cycle (Georgetown, Tex.) - 1 Jan 2009

Miao Zhi-Min, Zhao Shi-Hua, Yan Sheng-Li, Li Chang-Gui, Wang Yan-Gang, Meng Dong-Mei, Zhou Li, Mi Qing-Sheng

Abstract excerpt

Gout is the most common autoinflammatory arthritis characterized by elevated serum urate and recurrent attacks of intra-articular crystal deposition of monosodium urate (MSU). Although the pathogenesis of gout is still unclear, accumulated studies indicate that genetic factors trigger gout development, including some susceptibility genes that control the production and clearance of urate and lead to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carrier Proteins
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Inflammasome and immune disorders

Share to Inflammation

Share to Interleukin-1beta

Share to Polymorphism, Genetic

Share to Uric Acid

Source

Identifiers

PMID: 19106604
DOI: 10.4161/cc.8.1.7325

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NALP3 inflammasome functional polymorphisms and gout susceptibility.PMID 19106604Read ↗

The current role of NLRP3 inflammasome polymorphism in gout susceptibility.Semantic proximity Read ↗

The pathogenesis of gout: molecular insights from genetic, epigenomic and transcriptomic studies.Semantic proximity Read ↗

An update on the genetics of hyperuricaemia and gout.Semantic proximity Read ↗

The inflammasome, autoinflammatory diseases, and gout.Semantic proximity Read ↗

Role of NLRP3 in the pathogenesis and treatment of gout arthritis.Semantic proximity Read ↗

Multiplicative interaction of functional inflammasome genetic variants in determining the risk of gout.Semantic proximity Read ↗

Gene polymorphisms in the NALP3 inflammasome are associated with interleukin-1 production and severe inflammation: relation to common inflammatory diseases?Semantic proximity Read ↗

Inflammasome genes polymorphisms and susceptibility to gout. Is there a link?Semantic proximity Read ↗

Toll-Like receptor 4 (TLR4) polymorphism rs2149356 and risk of gout in a Spanish cohort.Semantic proximity Read ↗

Genetic variants of PPAR-gamma coactivator 1B augment NLRP3-mediated inflammation in gouty arthritis.Semantic proximity Read ↗

Crystal ball gazing: new therapeutic targets for hyperuricaemia and goutSemantic proximity Read ↗

Association of NLRP3 polymorphisms with susceptibility to primary gouty arthritis in a Chinese Han population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.