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Article

Association of NLRP3 polymorphisms with susceptibility to primary gouty arthritis in a Chinese Han population.

Clinical rheumatology - 1 Jan 2018

Zhang Quan-Bo, Qing Yu-Feng, He Yong-Long, Xie Wen-Guang, Zhou Jing-Guo

Abstract excerpt

The NLRP3-interleukin1β (IL1β) signaling pathway is involved in monosodium urate (MSU)-mediated inflammation. The aim of this present study was to determine whether single nucleotide polymorphisms (SNPs) in the NLRP3 gene are associated with susceptibility to gouty arthritis (GA) and whether these SNPs alter the expression of components of the NLRP3-IL1β signaling pathway. The rs10754558, rs4612666, and rs1539019...

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Source

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Identifiers

PMID: 29214547
DOI: 10.1007/s10067-017-3900-6
PMCID: PMC5754462

Genes

NLRP3
CGA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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