Article
Inflammasome genes polymorphisms and susceptibility to gout. Is there a link?
Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion - 2 May 2022
Clavijo-Cornejo Denise, López-Reyes Alberto, Cruz-Arenas Esteban, Jacobo-Albavera Leonor, Rivera-Tlaltzicapa Daniel, Francisco-Balderas Adriana, Domínguez-Pérez Mayra, Romero-Morelos Pablo, Vázquez-Mellado Janitzia, Silveira Luis H, Pineda Carlos, Martínez-Nava Gabriela, Gutierrez Marwin
Abstract excerpt
Background: The inflammatory response in gout disease is induced by the activation of NLR family pyrin domain-containing 3 (NLPR3) signaling pathway mediated by IL-1β release. Objective: The objective of the study was to determine the association between single nucleotide polymorphisms (SNPs) within NLRP3 inflammasome genes and gout susceptibility. Methods: Mexican patients with gout from the National...
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