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Article

Role of NLRP3 in the pathogenesis and treatment of gout arthritis.

Frontiers in immunology - 1 Jan 2023

Liu Ya-Ru, Wang Jie-Quan, Li Jun

Abstract excerpt

Gout arthritis (GA) is a common and curable type of inflammatory arthritis that has been attributed to a combination of genetic, environmental and metabolic factors. Chronic deposition of monosodium urate (MSU) crystals in articular and periarticular spaces as well as subsequent activation of innate immune system in the condition of persistent hyperuricemia are the core mechanisms of GA. As is well known, drugs...

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Identifiers

PMID: 37051231
DOI: 10.3389/fimmu.2023.1137822
PMCID: PMC10083392

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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