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Article

The H3.3K27M oncohistone antagonizes reprogramming in Drosophila.

PLoS genetics - 1 Jul 2021

Ahmad Kami, Henikoff Steven

Abstract excerpt

Development proceeds by the activation of genes by transcription factors and the inactivation of others by chromatin-mediated gene silencing. In certain cases development can be reversed or redirected by mis-expression of master regulator transcription factors. This must involve the activation of previously silenced genes, and such developmental aberrations are thought to underlie a variety of cancers. Here, we...

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Identifiers

PMID: 34280185
DOI: 10.1371/journal.pgen.1009225
PMCID: PMC8320987

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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