Article
CoREST acts as a positive regulator of Notch signaling in the follicle cells of Drosophila melanogaster.
Journal of cell science - 15 Jan 2012
Domanitskaya Elena, Schüpbach Trudi
Abstract excerpt
The Notch signaling pathway plays important roles in a variety of developmental events. The context-dependent activities of positive and negative modulators dramatically increase the diversity of cellular responses to Notch signaling. In a screen for mutations affecting the Drosophila melanogaster follicular epithelium, we isolated a mutation in CoREST that disrupts the Notch-dependent mitotic-to-endocycle switch...
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