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Article

Mendelian randomization analysis identified genes pleiotropically associated with central corneal thickness.

BMC genomics - 7 Jul 2021

Yang Zhikun, Yang Jingyun, Liu Di, Yu Weihong

Abstract excerpt

OBJECTIVE: To prioritize genes that were pleiotropically or potentially causally associated with central corneal thickness (CCT). METHODS: We applied the summary data-based Mendelian randomization (SMR) method integrating summarized data of genome-wide association study (GWAS) on CCT and expression quantitative trait loci (eQTL) data to identify genes that were pleiotropically associated with CCT. We performed...

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Identifiers

PMID: 34233613
DOI: 10.1186/s12864-021-07860-3
PMCID: PMC8263012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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