Article
A genome-wide association study of central corneal thickness in Latinos.
Investigative ophthalmology & visual science - 1 Apr 2013
Gao Xiaoyi, Gauderman W James, Liu Yutao, Marjoram Paul, Torres Mina, Haritunians Talin, Kuo Jane Z, Chen Yii-Der I, Allingham R Rand, Hauser Michael A, Taylor Kent D, Rotter Jerome I, Varma Rohit
Abstract excerpt
PURPOSE: Central corneal thickness (CCT) is a clinically important risk factor for primary open-angle glaucoma and keratoconus. Genetic factors controlling CCT in Latinos, the most populous minority population in the United States, are unclear. Here we describe the first genome-wide association study (GWAS) report of CCT in Latinos. METHODS: We performed a GWAS for CCT on 1768 Latinos recruited in the Los Angeles...
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