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Central corneal thickness and the risk of primary open-angle glaucoma: a Mendelian randomization mediation analysis

2023-11-29

Abstract excerpt

The association of central corneal thickness (CCT) with primary open-angle glaucoma (POAG) remains uncertain. Although, several observational studies assessing this relationship, have reported an inverse association between CCT and POAG, this could be the result of collider bias. In this study, we leveraged human genetic data to assess through Mendelian randomization (MR) the effect of CCT on POAG risk, and whethe...

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Literature Corpus work
8496c461-de06-5cc6-92f2-f6a3cbb328ac
DOI
10.1101/2023.11.28.23299139
Open publication

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Central corneal thickness and the risk of primary open-angle glaucoma: a Mendelian randomization mediation analysisDOI 10.1101/2023.11.28.23299139
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