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Article

A targeted approach to genome-wide studies reveals new genetic associations with central corneal thickness.

Molecular vision - 1 Jan 2017

Benson Matthew D, Khor Chiea C, Gage Philip J, Lehmann Ordan J

Abstract excerpt

Purpose: To evaluate the ability of a targeted genome-wide association study (GWAS) to identify genes associated with central corneal thickness (CCT). Methods: A targeted GWAS was used to investigate whether ten candidate genes with known roles in corneal development were associated with CCT in two Singaporean populations. The single nucleotide polymorphisms (SNPs) within a 500 kb interval encompassing each...

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Identifiers

PMID: 29296075
PMCID: PMC5741379

Genes

DKK2
DKK1
FOXO1
FZD8
RYK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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