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Article

Sex-Based Differences in Cardiac Gene Expression and Function in BDNF Val66Met Mice.

International journal of molecular sciences - 29 Jun 2021

Negron Marcus, Kristensen Jeffrey, Nguyen Van Thuan, Gansereit Lauren E, Raucci Frank J, Chariker Julia L, Heck Aaron, Brula Imamulhaq, Kitchen Gabrielle, Awgulewitsch Cassandra P, Zhong Lin, Rouchka Eric C, Banga Simran, Galindo Cristi L

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) is a pleiotropic neuronal growth and survival factor that is indispensable in the brain, as well as in multiple other tissues and organs, including the cardiovascular system. In approximately 30% of the general population, BDNF harbors a nonsynonymous single nucleotide polymorphism that may be associated with cardiometabolic disorders, coronary artery disease, and Duchenne...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34210092
DOI: 10.3390/ijms22137002
PMCID: PMC8269163

Genes

BDNF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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