Article
Impact of BDNF Val66Met Polymorphism on Myocardial Infarction: Exploring the Macrophage Phenotype.
Cells - 27 Apr 2020
Sandrini Leonardo, Castiglioni Laura, Amadio Patrizia, Werba José Pablo, Eligini Sonia, Fiorelli Susanna, Zarà Marta, Castiglioni Silvia, Bellosta Stefano, Lee Francis S, Sironi Luigi, Tremoli Elena, Barbieri Silvia Stella
Abstract excerpt
Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin growth factor family, well known for its role in the homeostasis of the cardiovascular system. Recently, the human BDNF Val66Met single nucleotide polymorphism has been associated with the increased propensity for arterial thrombosis related to acute myocardial infarction (AMI). Using cardiac magnetic resonance imaging and...
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