Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism affects sympathetic tone in a gender-specific way.

Psychoneuroendocrinology - 1 Sept 2014

Chang Chuan-Chia, Chang Hsin-An, Chen Tien-Yu, Fang Wen-Hui, Huang San-Yuan

Abstract excerpt

The Val/Val genotype of the brain-derived neurotrophic factor (BDNF) polymorphism (Val66Met) has been reported to affect human anxiety-related phenotypes. Substantial research has demonstrated that anxiety is associated with sympathetic activation, while sex steroid hormones have been shown to exert differential actions in regulating BDNF expression. Thus, we examined whether the BDNF variant modulates autonomic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to Anxiety

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brain-Derived Neurotrophic Factor

Share to Heart Rate

Share to Methionine

Share to Sympathetic Nervous System

Share to Valine

Share to Young Adult

Source

Identifiers

PMID: 25001952
DOI: 10.1016/j.psyneuen.2014.04.019

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism affects sympathetic tone in a gender-specific way.PMID 25001952Read ↗

BDNF Val66Met polymorphism alters sympathovagal balance in healthy subjects.Semantic proximity Read ↗

Sex-specific association between nerve growth factor polymorphism and cardiac vagal modulation.Semantic proximity Read ↗

BDNF Val66Met polymorphism is associated with HPA axis reactivity to psychological stress characterized by genotype and gender interactions.Semantic proximity Read ↗

The BDNF Val66Met polymorphism affects HPA-axis reactivity to acute stress.Semantic proximity Read ↗

Functional Ser205Leu polymorphism of the nerve growth factor receptor (NGFR) gene is associated with vagal autonomic dysregulation in humans.Semantic proximity Read ↗

Association of a functional BDNF polymorphism and anxiety-related personality traits.Semantic proximity Read ↗

BDNF Val66Met polymorphism and brain-derived neurotrophic factor levels across the female life span: implications for the sex bias in affective disorders.Semantic proximity Read ↗

Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism interacts with gender to influence cortisol responses to mental stress.Semantic proximity Read ↗

Serotonin receptor 1A promoter polymorphism, rs6295, modulates human anxiety levels via altering parasympathetic nervous activity.Semantic proximity Read ↗

Sex-Based Differences in Cardiac Gene Expression and Function in BDNF Val66Met Mice.Semantic proximity Read ↗

Association study of a brain-derived neurotrophic factor (Val66Met) genetic polymorphism and panic disorder.Semantic proximity Read ↗

Brain-Derived Neurotrophic Factor Val66Met Polymorphism Affects the Relationship Between an Anxiety-Related Personality Trait and Resting Regional Cerebral Blood Flow.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.