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Article

Generalization of a genetic risk score for time to first albuminuria in children with sickle cell anaemia: SCCRIP cohort study results.

British journal of haematology - 1 Jul 2021

Rashkin Sara R, Rampersaud Evadnie, Kang Guolian, Ataga Kenneth I, Hankins Jane S, Wang Winfred, Estepp Jeremie H, Weiss Mitchell J, Lebensburger Jeffrey, Zahr Rima S

Abstract excerpt

Albuminuria predicts kidney disease progression in individuals with sickle cell anaemia (SCA); however, earlier prediction of kidney disease with introduction of reno-protective therapies prior to the onset of albuminuria may attenuate disease progression. A genetic risk score (GRS) for SCA-related nephropathy may provide an improved one-time test for early identification of high-risk patients. We utilized a GRS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 34137022
DOI: 10.1111/bjh.17647
PMCID: PMC8282691

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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