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Article

Roles of APOBEC3 in hepatitis B virus (HBV) infection and hepatocarcinogenesis.

Bioengineered - 1 Dec 2021

Zhang Yuan, Chen Xiaorong, Cao Yajuan, Yang Zongguo

Abstract excerpt

APOBEC3 (A3) cytidine deaminases inhibit hepatitis B virus (HBV) infection and play vital roles in maintaining a variety of biochemical processes, including the regulation of protein expression and innate immunity. Emerging evidence indicates that the deaminated deoxycytidine biochemical activity of A3 proteins in single-stranded DNA makes them a double-edged sword. These enzymes can cause cellular genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34043485
DOI: 10.1080/21655979.2021.1931640
PMCID: PMC8806738

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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