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Article

Human cytidine deaminases facilitate hepatitis B virus evolution and link inflammation and hepatocellular carcinoma.

Cancer letters - 28 Feb 2014

Deng Yang, Du Yan, Zhang Qi, Han Xue, Cao Guangwen

Abstract excerpt

During hepatitis B virus (HBV)-induced hepatocarcinogenesis, chronic inflammation facilitates the evolution of hepatocellular carcinoma (HCC)-promoting HBV mutants. Cytidine deaminases, whose expression is stimulated by inflammatory cytokines and/or chemokines, play an important role in bridging inflammation and HCC. Through G-to-A hypermutation, cytidine deaminases inhibit HBV replication and facilitate the...

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Identifiers

PMID: 24120759
DOI: 10.1016/j.canlet.2013.09.041

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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