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Article

The interesting relationship between APOBEC3 deoxycytidine deaminases and cancer: a long road ahead.

Open biology - 1 Dec 2020

Granadillo Rodríguez Milaid, Flath Ben, Chelico Linda

Abstract excerpt

Cancer is considered a group of diseases characterized by uncontrolled growth and spread of abnormal cells and is propelled by somatic mutations. Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3) family of enzymes are endogenous sources of somatic mutations found in multiple human cancers. While these enzymes normally act as an intrinsic immune defence against viruses, they can also...

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Identifiers

PMID: 33292100
DOI: 10.1098/rsob.200188
PMCID: PMC7776566

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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