Article
The role of cytidine deaminases on innate immune responses against human viral infections.
BioMed research international - 1 Jan 2013
Vieira Valdimara C, Soares Marcelo A
Abstract excerpt
The APOBEC family of proteins comprises deaminase enzymes that edit DNA and/or RNA sequences. The APOBEC3 subgroup plays an important role on the innate immune system, acting on host defense against exogenous viruses and endogenous retroelements. The role of APOBEC3 proteins in the inhibition of viral infection was firstly described for HIV-1. However, in the past few years many studies have also shown evidence...
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