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Phenotypic Heterogeneity and Metastasis of Breast Cancer Cells

11 May 2021

Abstract excerpt

Abstract Although intratumoral genomic heterogeneity can impede cancer research and treatment, less is known about the effects of phenotypic heterogeneities. To investigate the role of cell migration heterogeneities in metastasis, we phenotypically sorted metastatic breast cancer cells into two subpopulations based on migration ability. Although migration is typically considered to be associated with metastasis,...

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PMID: 33975882
DOI: 10.1158/0008-5472.can-20-1799

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