Article
Heterogeneity of Circulating Tumor Cells in Breast Cancer: Identifying Metastatic Seeds.
International journal of molecular sciences - 2 Mar 2020
Menyailo Maxim E, Tretyakova Maria S, Denisov Evgeny V
Abstract excerpt
Metastasis being the main cause of breast cancer (BC) mortality represents the complex and multistage process. The entrance of tumor cells into the blood vessels and the appearance of circulating tumor cells (CTCs) seeding and colonizing distant tissues and organs are one of the key stages in the metastatic cascade. Like the primary tumor, CTCs are extremely heterogeneous and presented by clusters and individual...
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