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Cell Adhesiveness Serves as a Biophysical Marker for Metastatic Potential

19 Dec 2019

Abstract excerpt

Tumors are heterogeneous and composed of cells with different dissemination abilities. Despite significant effort, there is no universal biological marker that serves as a metric for metastatic potential of solid tumors. Common to disseminating cells from such tumors, however, is the need to modulate their adhesion as they detach from the tumor and migrate through stroma to intravasate. Adhesion strength is...

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PMID: 31857292
DOI: 10.1158/0008-5472.can-19-1794

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