Article
A biophysical model of Epithelial-Mesenchymal Transition uncovers the frequency and size distribution of Circulating Tumor Cell clusters across cancer types
2019-02-28
Abstract excerpt
The gain of cellular motility via the epithelial-mesenchymal transition (EMT) is considered crucial in the metastatic cascade. Cells undergoing EMT to varying extents are launched into the bloodstream as single circulating tumor cells (CTCs) or multi-cellular clusters. The frequency and size distributions of these multi-cellular clusters has been recently measured, but the underlying mechanisms enabling these diff...
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Identifiers and source
- Literature Corpus work
- 6be7e932-c950-5212-b073-7ed880e6803a
- DOI
- 10.1101/563049