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Mechanisms of Motility in Metastasizing Cells

12 May 2010

Abstract excerpt

Cell migration and invasion are critical parameters in the metastatic dissemination of cancer cells and the formation of metastasis, the major cause of death in cancer patients. Migratory cancer cells undergo dramatic molecular and cellular changes by remodeling their cell-cell and cell-matrix adhesion and their actin cytoskeleton, molecular processes that involve the activity of various signaling networks....

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PMID: 20460404
DOI: 10.1158/1541-7786.mcr-10-0139

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