Article

Investigating epithelial‐mesenchymal heterogeneity of tumors and circulating tumor cells with transcriptomic analysis and biophysical modeling

2021-03-01

Abstract excerpt

Abstract Cellular heterogeneity along the epithelial‐mesenchymal plasticity (EMP) spectrum is a paramount feature observed in tumors and circulating tumor cells (CTCs). High‐throughput techniques now offer unprecedented details on this variability at a single‐cell resolution. Yet, there is no current consensus about how EMP in tumors propagates to that in CTCs. To investigate the relationship between EMP‐associate...

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Literature Corpus work: 3517bec1-e5ec-5328-941f-ba780cb0809e
DOI: 10.1002/cso2.1015

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