Article

Maintenance of epithelial traits and resistance to mesenchymal reprogramming promote proliferation in metastatic breast cancer

2020-03-20

Abstract excerpt

Despite important advances in the treatment of breast cancer, the 5-year survival rate for patients with distant metastasis remains less than 30%. Metastasis is a complex, multi-step process beginning with local invasion and ending with the outgrowth of systemically disseminated cells into actively proliferating metastases that ultimately cause the destruction of vital organs. It is this last step that limits pati...

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Identifiers and source

Literature Corpus work: 25ef0f66-ae03-59f8-851c-74e58445b31a
DOI: 10.1101/2020.03.19.998823

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