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Article

DR2S: an integrated algorithm providing reference-grade haplotype sequences from heterozygous samples.

BMC bioinformatics - 10 May 2021

Klasberg Steffen, Schmidt Alexander H, Lange Vinzenz, Schöfl Gerhard

Abstract excerpt

BACKGROUND: High resolution HLA genotyping of donors and recipients is a crucially important prerequisite for haematopoetic stem-cell transplantation and relies heavily on the quality and completeness of immunogenetic reference sequence databases of allelic variation. RESULTS: Here, we report on DR2S, an R package that leverages the strengths of two sequencing technologies-the accuracy of next-generation...

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Share to Algorithms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33971817
DOI: 10.1186/s12859-021-04153-0
PMCID: PMC8111713

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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