Article
HLA-A, -B, -C, -DRB1 allele and haplotype frequencies of the Korean population and performance characteristics of HLA typing by next-generation sequencing.
HLA - 1 Mar 2021
Jekarl Dong Wook, Lee Gun Dong, Yoo Jae Bin, Kim Jung Rok, Yu Haein, Yoo Jaeeun, Lim Jihyang, Kim Myungshin, Kim Yonggoo
Abstract excerpt
INTRODUCTION: Human leukocyte antigen (HLA) identification at the allelic level is important for haematopoietic stem cell transplantation (HSCT). Next-generation sequencing (NGS) resolves ambiguous alleles by determining the phase of the polymorphisms. The aim of this study was to validate the so...
Topics
- Alleles
- Gene Frequency
- HLA-A Antigens
- HLA-B Antigens
- HLA-DRB1 Chains
- Haplotypes
- High-Throughput Nucleotide Sequencing
- Histocompatibility Testing
- Humans
- Republic of Korea